extended abstract 1. introduction the quality of life can be considered as an operational tool to measure the overall health and welfare. in general, the concept quality of life is affected by various factors constituting the foundation of the life dynamics. since the concept quality of urban life is multidimensional and complex, it could be used in urban planning when an appropriate and reliab...

the present paper aimed at assessing the effects of young people’s indicators of life skills. the theoretical foundation of this research was obtained from adler’s and the world health organization’s viewpoints on life skill and mental health. the method of this study was a survey (applied, descriptive and correlation), and the sample group consisted of young people aged 15-29 in hajiabad town ...

introduction: over twenty developed and developing countries have regions with endemic floursis, on the other hand tooth decay as an infectious disease in human societies is reported to occur due to the shortage of fluoride in water. since decayed, missing, and filled teeth dmft is considered a 52 -character indicator in health equity, the present research aims at studying the relationship betw...

Mitochondrial dysfunction is a hallmark of beta-amyloid (Abeta)-induced neuronal toxicity in Alzheimer's disease (AD). Here, we demonstrate that Abeta-binding alcohol dehydrogenase (ABAD) is a direct molecular link from Abeta to mitochondrial toxicity. Abeta interacts with ABAD in the mitochondria of AD patients and transgenic mice. The crystal structure of Abeta-bound ABAD shows substantial de...

Amyloid β peptide binding alcohol dehydrogenase (ABAD) decoy peptide (DP) can competitively antagonize binding of amyloid β peptide to ABAD and inhibit the cytotoxic effects of amyloid β peptide. Based on peptide aptamers, the present study inserted ABAD-DP into the disulfide bond of human thioredoxin (TRX) using molecular cloning technique to construct a fusion gene that can express the TRX1-A...

Amyloid beta (Aβ) binding alcohol dehydrogenase (ABAD) is a cellular cofactor for promoting (Aβ)-mediated mitochondrial and neuronal dysfunction, and cognitive decline in transgenic Alzheimer's disease (AD) mouse models. Targeting mitochondrial ABAD may represent a novel therapeutic strategy against AD. Here, we report the biological activity of small molecule ABAD inhibitors. Using in vitro su...

The aim of this paper is to provide a preliminary investigation of the factors that determine whether Malaysia's Tabung Haji customers in Eastern Malaysia will use or not a new facility introduced by the institution, namely Automated Teller Machine or ATM banking. As such, this study introduces the concept Tabung Haji ATM Banking (TAB). In order to explain the factors, this paper extends the ap...

The aim of this paper is to provide a preliminary investigation of the factors that determine whether Malaysia’s Tabung Haji customers in Eastern Malaysia will use or not a new facility introduced by the institution, namely Automated Teller Machine or ATM banking. As such, this study introduces the concept Tabung Haji ATM Banking (TAB). In order to explain the factors, this paper extends the ap...

Th is paper presents a cultural semantic analysis of the Japanese emotion terms ‘haji’ and ‘hazukashii’, made using the methodology of the Natural Semantic Metalanguage (NSM). Th e paper has three aims: (i) to pinpoint the conceptions of ‘haji’ and ‘hazukashii’ as emotion terms in Japanese language and culture; (ii) to highlight the diff erences in meaning with their typical English translation...

Patients with acute type B aortic dissection (ABAD) are often treated medically. However, ABAD is a potentially serious emergency if complicated by acute organ ischemia. The therapeutic strategy for ABAD with visceral malperfusion remains controversial. Because emergent surgery has a high mortality rate, emergent endovascular treatment can be performed instead. We report a case of endovascular ...